The Three Catecholics Benserazide, Catechol and Pyrogallol are GPR35 Agonists
نویسندگان
چکیده
منابع مشابه
The Three Catecholics Benserazide, Catechol and Pyrogallol are GPR35 Agonists
Nearly 1% of all clinically used drugs are catecholics, a family of catechol-containing compounds. Using label-free dynamic mass redistribution and Tango β-arrestin translocation assays, we show that several catecholics, including benserazide, catechol, 3-methoxycatechol, pyrogallol, (+)-taxifolin and fenoldopam, display agonistic activity against GPR35.
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ژورنال
عنوان ژورنال: Pharmaceuticals
سال: 2013
ISSN: 1424-8247
DOI: 10.3390/ph6040500